Household-based cluster investigations have not yet been conducted during ZIKV outbreaks in Puerto Rico or elsewhere. Such investigations would enable enhanced case finding and subsequent extrapolation of current rates of under-reporting of ZIKV disease cases (due either to lack of presentation for care, clinical misdiagnosis, or failure for cases to be reported), description of the symptomatology of infected individuals, and elucidation of risk factors for infection among the individuals included in the investigation, which may or may not be the same as those amongst the larger population. Findings from both passive surveillance data and household-based cluster investigations may provide a more informed interpretation of the community-wide patterns of ZIKV infections, and will be used to develop or refine messaging to the public and medical communities to improve case-seeking behavior and case reporting.
Emergency Clearance is requested to; 1) Conduct household-based cluster investigations in areas with and without ongoing community-wide vector control (e.g., aerial spraying) activities, and 2) Compare trends in ZIKV disease cases reported to the Passive Arboviral Diseases Surveillance System (PADSS) in areas with and without ongoing community-wide vector control activities (e.g., aerial spraying). Findings will be used to develop or refine messaging to the public and medical communities to improve case-seeking behavior and case reporting, respectively. It is not expected that this project will take longer than six months.
US Code:
42 USC 241
Name of Law: U.S. Public Health Service Act
Non-Substantive Change includes addition of new Form to collect information regarding the demographics of those who refuse to participate in the collection.
On behalf of this Federal agency, I certify that the collection of information encompassed by this request complies with 5 CFR 1320.9 and the related provisions of 5 CFR 1320.8(b)(3).
The following is a summary of the topics, regarding the proposed collection of information, that the certification covers:
(i) Why the information is being collected;
(ii) Use of information;
(iii) Burden estimate;
(iv) Nature of response (voluntary, required for a benefit, or mandatory);
(v) Nature and extent of confidentiality; and
(vi) Need to display currently valid OMB control number;
If you are unable to certify compliance with any of these provisions, identify the item by leaving the box unchecked and explain the reason in the Supporting Statement.
Refusal Demographics Form
0920-1137 change request.docx
Emergency Review Request Memo - Signed.pdf
Refusal Demographics Form